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  • Human TNF-beta/TNFSF1/Lymphotoxin alpha recombinant protein

Human TNF-beta/TNFSF1/Lymphotoxin alpha recombinant protein

Cat.#: 502418

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Product Information

  • Product Name
    Human TNF-beta/TNFSF1/Lymphotoxin alpha recombinant protein
  • Documents
  • Description
    Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
  • Protein name
    Lymphotoxin-alpha
  • Protein short names
    LT-ALPHA; LYMPHOTOXIN ALPHA; LT-[A]; TNFSF1B; LT; HLB382; LTALPHA; DAMA-25N12.13-004; TNF-BETA; TNFB; LT[A]; MGC117668; LTX; TNFSF1; LTA
  • Uniprot ID
    P01374
  • Gene Name
    LTA; TNFB; TNFSF1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human TNF? (P01374) (Leu 35-Leu 205) was expressed and purified, with an initial Met at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human TNF? comprises 172 amino acids and predicts a molecular mass of 18.8 kDa as estimated in SDS-PAGE under reducing conditions.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.1-0.5 ng/ml.
  • Validations

    Human TNF-beta / TNFSF1 / Lymphotoxin alpha Protein SDS-PAGE

    Human TNF-beta / TNFSF1 / Lymphotoxin alpha Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"