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Product Name
LTB4R Polyclonal Antibody
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Description
Polyclonal antibody to LTB4R
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Tested applications
WB
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Species reactivity
Mouse
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Alternative names
LTB4R antibody; BLT1 antibody; BLTR antibody; CMKRL1 antibody; GPR16 antibody; LTB4R1 antibody; LTBR1 antibody; P2RY7 antibody; P2Y7 antibody; leukotriene B4 receptor antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human LTB4R (NP_858043.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - LTB4R Polyclonal Antibody
Western blot analysis of extracts of Mouse thymus, using LTB4R antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.
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Background
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"