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Product Name
LSM4 antibody
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Description
LSM4 Rabbit Polyclonal antibody. Positive IHC detected in human lung cancer tissue. Positive WB detected in MCF7 cells, human placenta tissue, MDA-MB-231 cells. Observed molecular weight by Western-blot: 15 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Glycine rich protein antibody; GRP antibody; LSM4 antibody; YER112W antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LSM4 recombinant protein (Accession Number: NM_012321). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:112349(LSM4 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:112349(LSM4 antibody) at dilution of 1:100 (under 10x lens)
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Background
Sm-like proteins, such as LSM4, were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing
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References
- Berg MG, Wan L, Younis I. A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis. Molecular and cellular biology. 32(7):1271-83. 2012.
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