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Product Name
Recombinant LRRT4 protein (His tag)
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Description
The Recombinant Human LRRTM4 (33-362) Protein is a high-quality, 330-amino acid fragment of Leucine-rich repeat transmembrane neuronal protein 4, encompassing the functional LRRCT domain. This product is ideal for investigating synaptogenic activity and excitatory synapse development, offering researchers a precise tool for domain-specific functional studies.
Leucine-rich repeat transmembrane neuronal protein 4 (LRRTM4), encoded by the LRRTM4 gene in Homo sapiens, plays a critical role in the development and maintenance of the vertebrate nervous system. It exhibits strong synaptogenic activity, specifically promoting excitatory presynaptic differentiation, which is essential for neural circuit formation and function. The protein is localized to the cell membrane and postsynaptic cell membrane as a single-pass type I membrane protein, underscoring its importance in synaptic signaling and neuronal connectivity. This recombinant fragment allows focused exploration of these key biological processes.
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Protein name
Leucine-rich repeat transmembrane neuronal protein 4
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Uniprot ID
Q86VH4
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Gene Name
LRRTM4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 33-362 aa (Q86VH4) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 39.58 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 40 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"