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Product Name
Recombinant LRRC4 protein (His tag)
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Description
Recombinant Human LRRC4 Fragment (39-445) is a high-purity protein designed for studying synaptic adhesion and neural circuit formation. This 407-amino acid fragment encompasses key functional domains (LRRNT, LRRCT, and Ig-like), making it an ideal tool for investigating excitatory synapse regulation and dendritic differentiation in neurological research.
LRRC4 (Leucine-rich repeat-containing protein 4) is a synaptic adhesion protein that plays a critical role in organizing excitatory synapses through recruitment of pre- and postsynaptic proteins. It contributes to lamina-specific dendritic differentiation and is essential for auditory synaptic responses. Located in the postsynaptic cell membrane, LRRC4 forms interdependent localization complexes with proteins like DLG4. The protein also shows functional significance in glioma suppression, highlighting its importance in both normal neural development and pathological conditions.
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Protein name
Leucine-rich repeat-containing protein 4
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Uniprot ID
Q9HBW1
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Gene Name
LRRC4; BAG
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 39-445 aa (Q9HBW1) were fused with 6His tag.
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Sequence
39-445
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 47.38 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 47 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"