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  • LGR5 antibody
  • LGR5 antibody

LGR5 antibody

Cat.#: 112211

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Special Price 239.0 USD

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Product Information

  • Product Name
    LGR5 antibody
  • Documents
  • Description
    LGR5 Rabbit Polyclonal antibody. Positive IHC detected in human small intestine tissue, human colon cancer tissue, human colon tissue, human liver cancer tissue.
  • Tested applications
    ELISA, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    FEX antibody; G protein coupled receptor 49 antibody; G protein coupled receptor 67 antibody; GPR49 antibody; GPR67 antibody; GRP49 antibody; HG38 antibody; LGR5 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of LGR5 recombinant protein (Accession Number: BC096324). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    IHC: 1:20-1:200

  • Validations

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:112211(LGR5 antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:112211(LGR5 antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:112211(LGR5 antibody) at dilution of 1:200 (under 40x lens)

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:112211(LGR5 antibody) at dilution of 1:200 (under 40x lens)

  • Background
    LGR5, also named as GPR49, GPR67 and HG38, belongs to the G-protein coupled receptor 1 family. It is an orphan receptor. LGR5 is a stem cell marker of the intestinal epithelium and the hair follicule. It is a target gene of Wnt signaling.
  • References
    • Wang Y, Jiang CQ, Fan LF. Correlation of Musashi-1, Lgr5, and pEGFR expressions in human small intestinal adenocarcinomas. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 36(8):6075-82. 2015.
    • Vieira GC, Chockalingam S, Melegh Z. LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma. Oncotarget. 6(37):40053-67. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"