KL-7 peptide

KL-7 peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

Ac-KLVFFAL-NH2

Ac-Lys-Leu-Val-Phe-Phe-Ala-Leu-NH2

7

95.76%

C₄₆H₇₁N₉O₈

878.1

Synthetic

Powder

KL-7 is a heptapeptide, specifically Ac-KLVFFAL-NH2, that self-assembles into homogeneous peptide nanotubes at neutral pH. The nanotubes have a well-defined nanostructure, with an average length of a few micrometers and a diameter of 30-40 nm. The amino group of the lysine residue in KL-7 is exposed on the nanotube surface. The exposed amino group can react with carbon dioxide, resulting in the formation of carbamate and selective chemisorption of carbon dioxide. The KL-7 nanotube powder has good regeneration properties and is effective in the presence of water. The KL-7 nanotube is suitable for practical applications due to its mild regeneration temperature, low energy consumption requirements, and simple production process.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Geng R , Lu D , Lai Y , Wu S , Xu Z , Zhang W . Peptide nanotube for carbon dioxide chemisorption with regeneration properties and water compatibility. Chem Commun (Camb). 2019 Mar 26;55(26):3797-3800. doi: 10.1039/c9cc00495e. PMID: 30865202.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.