Jelleine-I peptide

Jelleine-I peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

PFKLSLHL-NH2

Pro-Phe-Lys-Leu-Ser-Leu-His-Leu-NH2

8

99.46%

C₄₇H₇₆N₁₂O₉

953.17

Synthetic

Powder

Active against G+ bacteria S. aureus ATCC 6535, S. saprophyticus, B. subtilis CCT 2471 (MIC 10-15 ug/ml), and G- bacteria E. coli CCT 1371 (MIC 2.5 ug/ml), E. cloacae ACCT 23355, K. pneumoniae ACCT 13883, P. aeruginsa ACCT 27853 (MIC 10 ug/ml), and yeast C. albicans (MIC 2.5 ug/ml). Jelleines are produced constitutively by the workers and secreted into Royal Jelly. This peptide can show synergistic killing of Gram-positive bacteria with temporin A or B (Romanelli A et al 2011 Peptides Jan 19. doi: 10.1002/psc.1316). Updated Jan 2011; 7/2014. Jelleine-I has Antibacterial, Antifungal activity. The source of Jelleine-I is honeybees, Apis mellifera.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Fontana R, Mendes MA, De souza BM, et al. Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera). Peptides. 2004;25(6):919-28.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.