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  • ITPKB antibody
  • ITPKB antibody

ITPKB antibody

Cat.#: 111958

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Special Price 239.0 USD

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Product Information

  • Product Name
    ITPKB antibody
  • Documents
  • Description
    ITPKB Rabbit Polyclonal antibody. Positive IHC detected in human cervical cancer tissue. Positive WB detected in mouse brain tissue, K-562 cells, mouse lung tissue, mouse thymus tissue, rat brain tissue. Observed molecular weight by Western-blot: 102-110 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse, Rat; other species not tested.
  • Alternative names
    InsP 3 kinase B antibody; IP3 3 kinase B antibody; IP3K antibody; IP3K B antibody; IP3KB antibody; ITPKB antibody; PIG37 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of ITPKB recombinant protein (Accession Number: BC015009). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:111958(ITPKB antibody) at dilution of 1:500

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:111958(ITPKB antibody) at dilution of 1:500

    Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using Catalog No:111958(ITPKB Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using Catalog No:111958(ITPKB Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Inositol 1,4,5-trisphosphate 3-kinase isoform B (IITPKB) is also named as IP3KB and possesses important roles in the development of immune cells. IP3KB can be targeted to multiple cellular compartments, among them nuclear localization and binding in close proximity to the plasma membrane. The B isoform is the only IP3K that is almost ubiquitously expressed in mammalian cells(PMID:21148483).Three isoforms of IP3KB occur in mammals, which are distinguished by different molecular masses, sensitivity to Ca2+/CaM(calmodulin), intracellular distribution and tissue expression (PMID:16173920).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"