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Product Name
Human IL13RA1/IL-13RA1 (His Tag) recombinant protein
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Description
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
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Protein name
Interleukin-13 receptor subunit alpha-1
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Protein short names
IL-13R[A]; RP13-128O4.2; RP23-132G2.1; IL-13RA; AI882074; IL13RA; NR4; CD213A1; IL13RA1
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Uniprot ID
P78552
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Gene Name
IL13RA1; IL13R; IL13RA
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human IL13R?1 (NP_001551.1) extracellular domain (Met 1-Thr 343) expressed, with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human IL13R?1 consists of 333 amino acids and has a predicted molecular mass of 38.3 kDa. As a result of glycosylation, the apparent molecular mass of rh IL13R?1 is approximately 55-65 kDa in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA. Immobilized human IL13RA1 at 4 μg/ml (100 μl/well) can bind human IL13 with a linear ranger of 0.156-2.5 μg/ml.
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Validations
Human IL13RA1 Protein (His Tag) SDS-PAGE
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