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Human Iduronate 2-Sulfatase / IDS (His Tag) recombinant protein

Cat.#: 501095

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Product Information

  • Product Name
    Human Iduronate 2-Sulfatase / IDS (His Tag) recombinant protein
  • Documents
  • Description
    Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
  • Protein name
    Iduronate 2-sulfatase
  • Protein short names
    IDURONATE 2-SULFATASE 42 KDA CHAIN; SIDS; IDS; MPS2; AW214631; IDURONATE SULFATASE; IDURSULFASE; IDURONATE 2-SULFATASE; RP23-29M4.1; ALPHA-L-IDURONATE SULFATE SULFATASE; IDURONATE 2-SULFATASE 14 KDA CHAIN
  • Uniprot ID
    P22304
  • Gene Name
    IDS; SIDS
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding human IDS precursor (NP_000193.1) (Met 1-Pro 550) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human IDS with the propeptide consists of 536 amino acids after removal of the signal peptide and has a predicted molecular mass of 61 kDa. In SDS-PAGE under reducing conditions, it migrates as several bands with apparent molecular mass between 85-95 KDa due to glycosylation.
  • Purity
    > 87 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to hydrolyze the substrate 4-Nitrocatechol Sulfate (PNCS).
    The specific activity is > 1.0 pmoles/min/μg.
  • Validations

    Human Iduronate 2-Sulfatase / IDS Protein (His Tag) SDS-PAGE

    Human Iduronate 2-Sulfatase / IDS Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"