Human VPS36 Recombinant protein (His tag)
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
Vacuolar protein-sorting-associated protein 36
Protein short names
VPS36; C13orf9; EAP45; CGI-145
1-386 aa encoded by BC050439 was inserted into T-HIS vector
Recombinant human VPS36(Full length) SDS-PAGE
Related Products / Services
- cDNA Clones
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