Human UROD (His tag) recombinant protein

Human UROD (His tag) recombinant protein

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Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).

uroporphyrinogen decarboxylase(UROD)

P06132

E.coli

A DNA sequence encoding the Human UROD Met1-Asn367 is expressed with a 6His tag at the N-terminus.

Human

>95% as determined by SDS-PAGE.