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  • Human TNFRSF4/TXGP1L (His tag) recombinant protein

Human TNFRSF4/TXGP1L (His tag) recombinant protein

Cat.#: 518664

Special Price 302.1 USD

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Product Information

  • Product Name
    Human TNFRSF4/TXGP1L (His tag) recombinant protein
  • Documents
  • Description
    OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
  • Protein name
    TNF receptor superfamily member 4(TNFRSF4)
  • Protein short names
    TXGP1L
  • Uniprot ID
    P43489
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human TNFRSF4/TXGP1L Leu29-Ala216 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human TNFRSF4/TXGP1L (His tag) recombinant protein

    Human TNFRSF4/TXGP1L (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"