Human RYR1 Recombinant protein (GST tag)

Human RYR1 Recombinant protein (GST tag)

• DataSheet
• Material Safety Data Sheets (MSDS)

Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity). {, PubMed:18268335}.

Ryanodine receptor 1

RYDR

P21817

RYR1; RYDR

E. coli

A DNA sequence encoding the human RYR1 (NP_000531.2) 4942-5038 aa was fused with the N-terminal GST tag

Human

Not tested.