Human RPE / RPE2-1 (His Tag) recombinant protein

Cat.#: 503579

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Product Information

  • Product Name
    Human RPE / RPE2-1 (His Tag) recombinant protein
  • Documents
  • Description
    The "ribulose phosphate binding" superfamily defined by the Structural Classification of Proteins (SCOP) database is considered the result of divergent evolution from a common (beta/alpha)(8)-barrel ancestor. The superfamily includes d-ribulose 5-phosphate 3-epimerase (RPE), orotidine 5'-monophosphate decarboxylase (OMPDC), and 3-keto-l-gulonate 6-phosphate decarboxylase (KGPDC). Replication of the human genome requires the activation of thousands of replicons distributed along each one of the chromosomes. Each replicon contains an initiation, or origin, site, at which DNA synthesis begins. In enzymology, a L-ribulose-5-phosphate 3-epimerase is an enzyme that catalyzes the chemical reaction L-ribulose 5-phosphate to L-xylulose 5-phosphate. Hence, RPE has one substrate, L-ribulose 5-phosphate, and one product, L-xylulose 5-phosphate. RPE belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is L-ribulose-5-phosphate 3-epimerase. Other names in common use include L-xylulose 5-phosphate 3-epimerase, UlaE, and SgaU.
  • Protein name
    Ribulose-phosphate 3-epimerase
  • Protein short names
    AC118589.1; 2810429B02RIK; MGC2636; RPE; HUSSY-17; RPE2-1; 5730518J08RIK
  • Uniprot ID
    Q96AT9
  • Gene Name
    RPE; HUSSY-17
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human RPE isoform 1 (NP_954699.1) (Ala 2-Arg 228) was expressed, with a polyhistidine tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human RPE consists of 246 amino acids and has a calculated molecular mass of 27 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhRPE is approximately 30 kDa.
  • Purity
    > 94 % as determined by SDS-PAGE
  • Validations

    Human RPE / RPE2-1 Protein (His Tag) SDS-PAGE

    Human RPE / RPE2-1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"