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Human PTGES3 Recombinant protein (GST tag)

Cat.#: 511659

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human PTGES3 Recombinant protein (GST tag)
  • Documents
  • Description
    Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448). {PubMed:10922363, PubMed:11274138, PubMed:12077419, PubMed:24711448}.
  • Protein name
    Prostaglandin E synthase 3
  • Protein short names
    P23; TEBP
  • Uniprot ID
    A0A087WYT3
  • Gene Name
    PTGES3; P23; TEBP
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human PTGES3 (NP_001269533.1) 6-164 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human PTGES3(Full length) SDS-PAGE

    Recombinant human PTGES3(Full length) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"