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  • Human PDZK1 Recombinant protein (His tag)

Human PDZK1 Recombinant protein (His tag)

Cat.#: 511084

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Product Information

  • Product Name
    Human PDZK1 Recombinant protein (His tag)
  • Documents
  • Description
    A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
  • Protein name
    Na(+/H(+ exchange regulatory cofactor NHE-RF3
  • Protein short names
    CAP70; NHERF3; PDZD1
  • Uniprot ID
    Q5T2W1
  • Gene Name
    PDZK1; CAP70; NHERF3; PDZD1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    1-300 aa encoded by NM_001201325 was inserted into PET28a vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human PDZK1 SDS-PAGE

    Recombinant human PDZK1 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"