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Product Name
Human PDGF-B/PDGF-2 (His Tag) recombinant protein
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Description
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
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Protein name
Platelet-derived growth factor subunit B
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Protein short names
PDGF2; SIS
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Uniprot ID
P01127
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Gene Name
PDGFB; PDGF2; SIS
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Source/Expression Host
Yeast
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Expression Plasmid/cDNA
A DNA sequence encoding the human PDGFB (NP_148937.1) (Ser82-Thr190) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PDGFB consists of 124 amino acids and predicts a molecular mass of 14.3 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"