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Product Name
Human PALLD,palladin Recombinant protein (GST tag)
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Description
Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci. {PubMed:11598191, PubMed:15147863, PubMed:17537434}.
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Protein name
Palladin
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Protein short names
KIAA0992
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Uniprot ID
Q8WX93
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Gene Name
PALLD; KIAA0992; CGI-151
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PALLD (XP_054205314.1) 1085-1468 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human PALLD,palladin SDS-PAGE
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