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Product Name
Human MINPP1/MIPP/UNQ900/PRO1917 (His tag) recombinant protein
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Description
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
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Protein name
multiple inositol-polyphosphate phosphatase 1(MINPP1)
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Protein short names
MIPP; UNQ900; PRO1917
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Uniprot ID
Q9UNW1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human MINPP1/MIPP/UNQ900/PRO1917 Ser31-Leu487 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human MINPP1/MIPP/UNQ900/PRO1917 (His tag) recombinant protein
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