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Product Name
Human MCL1/BCL2L3 (His tag) recombinant protein
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Description
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) is a member of the Bcl-2 family. MCL1 takes part in the control of apoptosis against cell existence, and in the preservation of viability but not of proliferation. MCL1 Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. It mediates its effects by interactions with a number of other regulators of apoptosis. Alternative splicing happens at this locus and two transcript variants encoding different isoforms are known. Isoform 1 is the longer gene product and it increases cell existence by inhibiting apoptosis. Isoform 2 is a shorter gene product which indorses apoptosis and is death-inducing.
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Protein name
BCL2 family apoptosis regulator(MCL1)
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Protein short names
BCL2L3
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Uniprot ID
Q07820
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human MCL1/BCL2L3 Met1-Gly327 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human MCL1/BCL2L3 (His tag) recombinant protein
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