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Product Name
Human IL21R/NILR/UNQ3121/PRO10273 (His tag) recombinant protein
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Description
Interleukin-21 receptor is also known as IL-21 receptor, IL-21R, CD360. In humans, it is encoded by the IL21R gene. It belongs to the type I cytokine receptor family. Type 4 subfamily contains 2 fibronectin type-III domains. Interleukin-21 receptor is selectively expressed in lymphoid tissues and highly expressed in thymus and spleen. IL-21 is produced by CD4+ T cells in response to antigenic stimulation. Its action enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells. It also promotes the anti-tumor activity of CD8+ T-cells and NK cells.
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Protein name
interleukin 21 receptor(IL21R)
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Protein short names
NILR; UNQ3121; PRO10273
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Uniprot ID
Q9HBE5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IL21R/NILR/UNQ3121/PRO10273 Cys20-Pro236 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human IL21R/NILR/UNQ3121/PRO10273 (His tag) recombinant protein
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