Human IL1RAP/C3orf13/IL1R3 (His tag) recombinant protein

Cat.#: 519804

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Product Information

  • Product Name
    Human IL1RAP/C3orf13/IL1R3 (His tag) recombinant protein
  • Documents
  • Description
    Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
  • Protein name
    interleukin 1 receptor accessory protein(IL1RAP)
  • Protein short names
    C3orf13; IL1R3
  • Uniprot ID
    Q9NPH3
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IL1RAP/C3orf13/IL1R3 Ser21-Gln356 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IL1RAP/C3orf13/IL1R3 (His tag) recombinant protein

    Human IL1RAP/C3orf13/IL1R3 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"