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Product Name
Human IL17B/IL20/NIRF/ZCYTO7 (Fc tag) recombinant protein
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Description
Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. In addition to IL-17B, members of the IL-17 family include IL-17A, IL-17C, IL-17D, IL-17E and IL-17F. The six IL-17 cytokines are highly conserved at C terminus, and contain five spatially conserved cysteine residues that mediate dimerization. Expression of IL-17B protein has been reported in neurons, testis, ovary, stomach, pancreas, small intestine and chondrocytes. IL-17B binds to Interleukine-17 receptor B (IL-17 RB) and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells.
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Protein name
interleukin 17B(IL17B)
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Protein short names
IL20; NIRF; ZCYTO7; UNQ516; PRO1031
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Uniprot ID
Q9UHF5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IL17B/IL20/NIRF/ZCYTO7 Gln21-Phe180 is expressed with a Fc tag at the C-terminus.
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Protein Species
Human
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Purity
>96% as determined by SDS-PAGE.
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Validations
Human IL17B/IL20/NIRF/ZCYTO7 (Fc tag) recombinant protein
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