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Human GRIN2B Recombinant protein (His tag)

Cat.#: 508423

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human GRIN2B Recombinant protein (His tag)
  • Documents
  • Description
    NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
  • Protein name
    Glutamate receptor ionotropic, NMDA 2B
  • Protein short names
    NMDAR2B
  • Uniprot ID
    Q13224
  • Gene Name
    GRIN2B; NMDAR2B
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human GRIN2B (XP_054227830.1) 1133-1484 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human GRIN2B SDS-PAGE

    Recombinant human GRIN2B SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"