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Product Name
Human GCA/GCL (GST tag) recombinant protein
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Description
Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions, which suggested a role for grancalcin in granule-membrane fusion and degranulation.
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Protein name
grancalcin(GCA)
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Protein short names
GCL
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Uniprot ID
P28676
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human GCA/GCL Met1-Ile217 is expressed with a GST tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human GCA/GCL (GST tag) recombinant protein
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