Human FcRn & B2M Heterodimer (His tag) recombinant protein

Cat.#: 519256

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Product Information

  • Product Name
    Human FcRn & B2M Heterodimer (His tag) recombinant protein
  • Documents
  • Description
    FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51(alpha chain) and Beta-2-microglobulin(Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).
  • Protein name
    IgG receptor FcRn and Beta-2-microglobulin
  • Uniprot ID
    P55899&P61769
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human FcRn & B2M Heterodimer Ala24-Leu290&Ile21-Met119 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human FcRn & B2M Heterodimer (His tag) recombinant protein

    Human FcRn & B2M Heterodimer (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"