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Product Name
Human DEFB4A/DEFB102/DEFB2/DEFB4/DEFB4B recombinant protein
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Description
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.
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Protein name
defensin beta 4B(DEFB4B)
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Protein short names
DEFB102; DEFB2; DEFB4; DEFB4B
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Uniprot ID
O15263
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human DEFB4A/DEFB102/DEFB2/DEFB4/DEFB4B Gly24-Pro64 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human DEFB4A/DEFB102/DEFB2/DEFB4/DEFB4B recombinant protein
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