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Product Name
Human DCK (His tag) recombinant protein
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Description
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.
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Protein name
deoxycytidine kinase(DCK)
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Uniprot ID
P27707
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human DCK Met1-Leu260 is expressed with a 6His, T7 tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human DCK (His tag) recombinant protein
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