Human CRCP Recombinant protein (His tag)

Human CRCP Recombinant protein (His tag)

• DataSheet
• Material Safety Data Sheets (MSDS)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).; Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.

DNA-directed RNA polymerase III subunit RPC9

O75575

CRCP

E. coli

A DNA sequence encoding the human CRCP (NP_001135886.1) 28-141 aa was fused with the polyhistidine tag

Human

Not tested.