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  • Human CNGA3 Recombinant protein (GST tag)

Human CNGA3 Recombinant protein (GST tag)

Cat.#: 506698

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Product Information

  • Product Name
    Human CNGA3 Recombinant protein (GST tag)
  • Documents
  • Description
    Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. {, PubMed:10888875}.
  • Protein name
    Cyclic nucleotide-gated cation channel alpha-3
  • Protein short names
    CNCG3
  • Uniprot ID
    Q16281
  • Gene Name
    CNGA3; CNCG3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    590-694 aa encoded by NM_001298 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human CNGA3 SDS-PAGE

    Recombinant human CNGA3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"