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Product Name
Human CGB5/CG-beta (Fc Tag) recombinant protein
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Description
CGB7 (chorionic gonadotropin, beta polypeptide 7) belongs to the glycoprotein hormones subunit beta family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CGB7 gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. CGB7 is used as adjunctive therapy in the treatment of obesity. CGB7 also stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
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Protein name
Choriogonadotropin subunit beta
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Protein short names
CGB6
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Uniprot ID
P01233
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Gene Name
CGB; CGB3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CGB5 (NP_000728.1) (Met1-Gln165) was expressed with the Fc region of mouse IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CGB5/mFc comprises 379 amino acids and has a predicted molecular mass of 41.9 kDa. The apparent molecular mass of the monomer is approximately 56 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human CGB5 Protein (Fc Tag) SDS-PAGE
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