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Product Name
Human CFHR5/CFHL5/FHR5 (His tag) recombinant protein
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Description
Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.
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Protein name
complement factor H related 5(CFHR5)
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Protein short names
CFHL5; FHR5
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Uniprot ID
Q9BXR6
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CFHR5/CFHL5/FHR5 Glu19-Glu569 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CFHR5/CFHL5/FHR5 (His tag) recombinant protein
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