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Product Name
Human CCL8/MCP2/SCYA10/SCYA8 (His tag) recombinant protein
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Description
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.
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Protein name
C-C motif chemokine ligand 8(CCL8)
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Protein short names
MCP2; SCYA10; SCYA8
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Uniprot ID
P80075
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CCL8/MCP2/SCYA10/SCYA8 Gln24-Pro99 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CCL8/MCP2/SCYA10/SCYA8 (His tag) recombinant protein
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