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Product Name
Human APOA1 recombinant protein
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Description
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.
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Protein name
apolipoprotein A1(APOA1)
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Uniprot ID
P02647
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human APOA1 Arg19-Gln267 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human APOA1 recombinant protein
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