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Product Name
Human AMIGO2/ALI1 (His tag) recombinant protein
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Description
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.
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Protein name
adhesion molecule with Ig like domain 2(AMIGO2)
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Protein short names
ALI1
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Uniprot ID
Q86SJ2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human AMIGO2/ALI1 Val40-His393 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human AMIGO2/ALI1 (His tag) recombinant protein
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