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Product Name
Recombinant HUM6 protein (His tag)
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Description
Recombinant Unconventional myosin heavy chain 6 (hum-6) fragment from Caenorhabditis elegans, encompassing amino acids 1062-1556. This 495-residue fragment contains key functional domains (Ras-associating, FERM 1, SH3), making it an ideal tool for studying intracellular movement mechanisms and domain-specific interactions in actin-based motor protein research.
Unconventional myosins are actin-based motor molecules that utilize ATP hydrolysis to drive intracellular movements. As actin-dependent motors, these proteins function in transporting membranous compartments within the cytoplasm, with their highly divergent tail regions mediating specific membrane binding. The full-length Unconventional myosin heavy chain 6 localizes to the cytoplasm where it participates in essential intracellular transport processes. This recombinant fragment specifically targets the protein's functional domains to enable focused investigation of their roles in membrane compartment movement and actin filament interactions.
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Protein name
Unconventional myosin heavy chain 6
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Uniprot ID
P91443
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Gene Name
hum-6
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1062-1556 aa (P91443) were fused with 6His tag.
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Protein Species
Caenorhabditis elegans
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Molecular weight
Predictes a molecular mass of 58.00 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 59 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"