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Product Name
HPS1 antibody
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Description
HPS1 Rabbit Polyclonal antibody. Positive WB detected in L02 cells, HEK-293 cells, K-562 cells, Raji cells, Transfected HEK-293 cells, Y79 cells. Observed molecular weight by Western-blot: 70-79 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
Hermansky Pudlak syndrome 1 antibody; HPS antibody; HPS1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of HPS1 recombinant protein (Accession Number: NM_182639). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:111451(HPS1 antibody) at dilution of 1:800
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Background
HPS1, also named as Hermansky-Pudlak syndrome 1 protein, is a 700 amino acid protein, which is a component of multiple cytoplasmic organelles. HPS1 is Apparently crucial for their normal development and function and involved in intracellular protein sorting.HPS1 is involved in the biogenesis of early melanosomes.
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References
- Cullinane AR, Yeager C, Dorward H. Dysregulation of galectin-3. Implications for Hermansky-Pudlak syndrome pulmonary fibrosis. American journal of respiratory cell and molecular biology. 50(3):605-13. 2014.
- Ikawa Y, Hess R, Dorward H. In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer. Molecular genetics and metabolism. 114(1):62-5. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"