Recombinant HPPD protein (His tag)

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• Material Safety Data Sheets (MSDS)

Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase (HPD) Fragment (aa 2-393) is a high-purity protein designed for functional studies. This fragment encompasses the full VOC 1 and VOC 2 domains, making it an ideal tool for investigating tyrosine catabolism and enzyme mechanisms in a controlled experimental setting.

4-Hydroxyphenylpyruvate Dioxygenase (HPD) is a key enzyme in tyrosine catabolism, catalyzing the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid. This reaction is essential for the breakdown of tyrosine, and disruptions in this pathway are linked to metabolic disorders. In humans, HPD is localized to the cytoplasm and is peripherally associated with the endoplasmic reticulum and Golgi apparatus membranes, indicating its involvement in compartmentalized metabolic processes. The recombinant fragment (aa 2-393) retains critical functional domains, enabling focused research on its catalytic activity and regulatory roles.