Mouse FcERI / FCER1A (Fc Tag) recombinant protein

Cat.#: 502450

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Product Information

  • Product Name
    Mouse FcERI / FCER1A (Fc Tag) recombinant protein
  • Documents
  • Description
    Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
  • Protein name
    High affinity immunoglobulin epsilon receptor subunit alpha
  • Protein short names
    FCEPSILONRI; IMMUNOGLOBULIN E RECEPTOR; FCR-5; FC-EPSILON RI-ALPHA; FC EPSILON RI ALPHA-CHAIN; ALPHA POLYPEPTIDE; HIGH-AFFINITY; RP11-550P17.3; FCERI; FC IGE RECEPTOR; IGE FC RECEPTOR SUBUNIT ALPHA; OF MAST CELLS; FCE1A; HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA; HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT
  • Uniprot ID
    P20489
  • Gene Name
    Fcer1a; Fce1a
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse FCER1A (P20489) (Met1-Gln204) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse FCER1A /Fc is a disulfide-linked homodimer. The reduced monomer comprises 422 amino acids and has a predicted molecular mass of 48 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Validations

    Mouse FcERI / FCER1A Protein (Fc Tag) SDS-PAGE

    Mouse FcERI / FCER1A Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"