GLRA2 antibody

Cat.#: 111031

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    GLRA2 antibody
  • Documents
  • Description
    GLRA2 Rabbit Polyclonal antibody. Positive WB detected in PBMC cells. Positive IHC detected in mouse brain tissue. Observed molecular weight by Western-blot: 48 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    GLR antibody; GLRA2 antibody; glycine receptor antibody; alpha 2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of GLRA2 recombinant protein (Accession Number: NM_001118885). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:300-1:1200

    IHC: 1:20-1:200

  • Validations

    WB result of GLRA2 antibody (Catalog No:111031, 1:600) with PBMC cells. Proteintech αGLRA2 Catalog No:111031 in 10% BSA / TBS 0.05% Tween-20 O/N @ 4°C Goat anti-rabbit HRP 1:10000 in 5% milk / TBS 0.05% Tween-20 1h @ RT.

    WB result of GLRA2 antibody (Catalog No:111031, 1:600) with PBMC cells. Proteintech αGLRA2 Catalog No:111031 in 10% BSA / TBS 0.05% Tween-20 O/N @ 4°C Goat anti-rabbit HRP 1:10000 in 5% milk / TBS 0.05% Tween-20 1h @ RT.

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:111031(GLRA2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:111031(GLRA2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:111031(GLRA2 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:111031(GLRA2 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified. (PMID: 11409700; 15383648)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"