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Recombinant GILT protein (His tag)

Recombinant GILT protein (His tag)

Cat.#: 537521

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Special Price 294.7 USD

Availability: 3-4 weeks
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Product Information

  • Product Name
    Recombinant GILT protein (His tag)
  • Documents
  • Description

    Recombinant human Gamma-interferon-inducible lysosomal thiol reductase (IFI30) fragment (amino acids 58-232) is a stable and soluble protein unit ideal for structural studies, biochemical assays, and research on antigen processing pathways.

    Gamma-interferon-inducible lysosomal thiol reductase (IFI30) is a lysosomal enzyme that reduces protein disulfide bonds, facilitating protein unfolding for lysosomal degradation. It plays a critical role in antigen processing by reducing disulfide bonds in antigens, enabling the generation of MHC class II-restricted epitopes and supporting MHC class I-restricted recognition of exogenous antigens through cross-presentation. The protein is localized to lysosomes and can also be secreted, underscoring its importance in immune response mechanisms.

  • Protein name
    Gamma-interferon-inducible lysosomal thiol reductase
  • Uniprot ID
    P13284
  • Gene Name
    IFI30; GILT; IP30
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 58-232 aa (P13284) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 21.58 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 23 kDa band.
  • Purity
    >86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"