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Product Name
Recombinant FXRD1 protein (His tag)
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Description
Recombinant human FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) fragment (residues 83-486) is a high-purity, stable protein designed for structural and functional studies. This 404-amino acid fragment retains key biochemical properties, making it ideal for investigating mitochondrial complex I assembly mechanisms and enzymatic activity.
FOXRED1 is a mitochondrial inner membrane protein essential for the assembly of NADH dehydrogenase (Complex I), a critical component of the mitochondrial respiratory chain. It functions during mid-late stages of complex I biogenesis, contributing to oxidative phosphorylation and cellular energy production. While its precise enzymatic activity (EC 1.-.-.-) requires further characterization, FOXRED1's role in mitochondrial function underscores its relevance to metabolic studies and neurodegenerative disease research. The selected soluble fragment (83-486) enables focused analysis of its structural and functional domains without transmembrane region complications.
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Protein name
FAD-dependent oxidoreductase domain-containing protein 1
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Uniprot ID
Q96CU9
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Gene Name
FOXRED1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 83-486 aa (Q96CU9) were fused with 6His tag.
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Sequence
83-486
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 46.50 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 47 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"