-
Product Name
Recombinant FOXM1 protein (His tag)
- Documents
-
Description
Recombinant Human FOXM1 Protein Fragment (234-325) - A highly stable and soluble fragment of the Forkhead box protein M1 transcription factor, ideal for structural studies and biochemical characterization of this critical cell cycle regulator.
Forkhead box protein M1 (FOXM1) is a key transcription factor that regulates the expression of cell cycle genes essential for DNA replication and mitosis. It plays a crucial role in controlling cell proliferation and participates in DNA break repair through the DNA damage checkpoint response. FOXM1 also promotes transcription of PHB2 and is exclusively localized in the nucleus, where it exerts its transcriptional regulatory functions. The full-length protein is involved in fundamental cellular processes including cell cycle progression, proliferation control, and DNA damage response mechanisms.
-
Protein name
Forkhead box protein M1
-
Uniprot ID
Q08050
-
Gene Name
FOXM1; FKHL16; HFH11; MPP2; WIN
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
DNA encoding 234-325 aa (Q08050) were fused with 6His tag.
-
Protein Species
Human
-
Molecular weight
Predictes a molecular mass of 12.69 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 13 kDa band.
-
Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
-
Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"