FLNC Polyclonal Antibody

Cat.#: 161391

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Product Information

  • Product Name
    FLNC Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to FLNC
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse
  • Alternative names
    FLNC antibody; ABP-280 antibody; ABP280A antibody; ABPA antibody; ABPL antibody; CMH26 antibody; FLN2 antibody; MFM5 antibody; MPD4 antibody; RCM5 antibody; filamin-C antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 2160-2340 of human FLNC (NP_001449.3).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • Validations

    Western blot - FLNC Polyclonal Antibody

    Western blot - FLNC Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using FLNC antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 1s.

    Immunofluorescence - FLNC Polyclonal Antibody

    Immunofluorescence - FLNC Polyclonal Antibody

    Immunofluorescence analysis of HeLa cells using FLNC antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

  • Background
    Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"