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Product Name
Mouse FGFRL1 / FGFR5 (His Tag) recombinant protein
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Description
Has a negative effect on cell proliferation.
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Protein name
Fibroblast growth factor receptor-like 1
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Protein short names
FGFR-5; FGFRL1; FGFR5GAMMA; FHFR; FGFR5BETA; FGFR5
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Uniprot ID
Q91V87
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Gene Name
Fgfrl1; Fgfr5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of mouse FGFRL1 (NP_473412.1) (Met 1-Pro 374) precursor was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse FGFRL1 consists of 365 amino acids and has a calculated molecular mass of 40.4 kDa. The apparent molecular mass of rmFGFRL1 is approximately 55-60 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
1. Immobilized mouse at 10 μg/ml (100 μl/well) can bind mouse FGFR5. The EC50 of mouse FGFR5 is 0.34 μg/ml.
2. Immobilized human FGF1 at 10 μg/ml (100 μl/well) can bind mouse FGFR5 with a linear range of 0.08-2 μg/ml.
3. Immobilized human bFGF at 5 μg/ml (100 μl/well) can bind mouse FGFR5. The EC50 of mouse FGFR5 is 0.22 μg/ml. -
Validations
Mouse FGFRL1 / FGFR5 Protein (His Tag) SDS-PAGE
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