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Product Name
Recombinant ERP29 protein (His tag)
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Description
This product is a recombinant fragment of human Endoplasmic reticulum resident protein 29 (ERp29), spanning residues 34-261. This 228-amino acid fragment has been computationally optimized for stability and solubility, making it an ideal tool for structural studies and biochemical assays focused on ERp29's role in protein folding within the secretory pathway.
Endoplasmic reticulum resident protein 29 (ERp29) is a key player in the processing of secretory proteins within the endoplasmic reticulum (ER), where it is primarily localized. Although it does not function as a disulfide isomerase, ERp29 is believed to contribute to the folding of proteins in the ER lumen, facilitating proper maturation and trafficking. It has also been identified in melanosomes, suggesting potential roles in pigment cell biology. The full-length protein's involvement in ER quality control and secretion underscores its importance in cellular homeostasis and protein biogenesis.
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Protein name
Endoplasmic reticulum resident protein 29
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Uniprot ID
P30040
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Gene Name
ERP29; C12orf8; ERP28
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 34-261 aa (P30040) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 27.40 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 29 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"