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  • EIF3H antibody

EIF3H antibody

Cat.#: 110196

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Special Price 239.0 USD

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Product Information

  • Product Name
    EIF3H antibody
  • Documents
  • Description
    EIF3H Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells. Observed molecular weight by Western-blot: 40kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    human, mouse, rat; other species not tested.
  • Alternative names
    EIF3H antibody; eIF 3 gamma antibody; eIF3 p40 subunit antibody; eIF3 gamma antibody; EIF3S3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of EIF3H recombinant protein (Accession Number: BC000386). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:110196(EIF3H antibody) at dilution of 1:500

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:110196(EIF3H antibody) at dilution of 1:500

  • Background
    Eukaryotic translation initiation factor eIF3, that plays a central role in translation initiation, consists of five core subunits that are present in both the budding yeast and higher eukaryotes. The EIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex. The complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. It is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3H is a component of the EIF3 complex. [PMID:19204574,20503360]
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"