EIF3H Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells. Observed molecular weight by Western-blot: 40kd
human, mouse, rat; other species not tested.
EIF3H antibody; eIF 3 gamma antibody; eIF3 p40 subunit antibody; eIF3 gamma antibody; EIF3S3 antibody
This antibody was obtained by immunization of EIF3H recombinant protein (Accession Number: BC000386). Purification method: Antigen affinity purified.
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Store at -20℃. DO NOT ALIQUOT
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:110196(EIF3H antibody) at dilution of 1:500
Eukaryotic translation initiation factor eIF3, that plays a central role in translation initiation, consists of five core subunits that are present in both the budding yeast and higher eukaryotes. The EIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex. The complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. It is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3H is a component of the EIF3 complex. [PMID:19204574,20503360]
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