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Human CLK3 (GST Tag) recombinant protein

Cat.#: 503043

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Special Price 353.3 USD

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Product Information

  • Product Name
    Human CLK3 (GST Tag) recombinant protein
  • Documents
  • Description
    Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
  • Protein name
    Dual specificity protein kinase CLK3
  • Protein short names
    MGC36552; FLJ22858; AI256811; PHCLK3/152; PHCLK3; CLK3; MGC103028
  • Uniprot ID
    P49761
  • Gene Name
    CLK3
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human CLK3 isoform b (NP_003983.2) (Met 1-Arg 490) was fused with the GST tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CLK3/GST chimera consists of 714 amino acids and predicts a molecular mass of 85 kDa. It migrates as an approxiamtely 70 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 89 % as determined by SDS-PAGE
  • Activity
    No Kinase Activity
  • Validations

    Human CLK3 Protein (GST Tag) SDS-PAGE

    Human CLK3 Protein (GST Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"